Tucuxi Drug Model Writing

Contents:

• Introduction
• Selecting a model
• Writing a Tucuxi drug model
  • Tucuxi Drug File Editor
  • Must read (general considerations)
  • General structure
  • History
  • Head
  • Drug Model
  • Domain
  • Covariates
  • Active moiety
  • Analyte groups
  • Parameters
  • Formulation and route
  • Dosages
  • Time considerations
  • List of units
• Validating a Tucuxi drug model
• Tucuxi PK models
  • Linear elimination, 1 compartment, macro constants
  • Linear elimination, 1 compartment, micro constants
  • Linear elimination, 2 compartments, macro constants
  • Linear elimination, 2 compartments, micro constants
  • Linear elimination, 2 compartments, macro constants, with Q and V2 as ratios of CL and V1
  • Linear, 3 compartments, macro constants
  • Linear, 3 compartments, micro constants
  • Linear, 2 compartments, erlang absorption with 1 transit compartment, macro constants
  • Linear, 2 compartments, erlang absorption with 1 transit compartment, micro constants
  • Linear, 2 compartments, erlang absorption with 2 transit compartment, macro constants
  • Linear, 2 compartments, erlang absorption with 2 transit compartment, micro constants
  • Linear, 2 compartments, erlang absorption with 3 transit compartment, macro constants
  • Linear, 2 compartments, erlang absorption with 3 transit compartment, micro constants
  • Linear, 2 compartments, erlang absorption with 4 transit compartment, macro constants
  • Linear, 2 compartments, erlang absorption with 4 transit compartment, micro constants
  • Linear, 2 compartments, erlang absorption with 5 transit compartment, macro constants
  • Linear, 2 compartments, erlang absorption with 5 transit compartment, micro constants
  • Linear, 2 compartments, erlang absorption with 6 transit compartment, macro constants
  • Linear, 2 compartments, erlang absorption with 6 transit compartment, micro constants
  • Michaelis-Menten, 1 compartment
  • Michaelis-Menten, 1 compartment, with Vmax as an amount
  • Michaelis-Menten and linear elimination, 1 compartment, macro constants
  • Michaelis-Menten and linear elimination, 1 compartment, micro constants
  • Michaelis-Menten and linear elimination, 1 compartment, with Vmax as an amount, macro constants
  • Michaelis-Menten and linear elimination, 1 compartment, micro constants
  • Michaelis-Menten, 2 compartments, macro constants
  • Michaelis-Menten, 2 compartments, micro constants
  • Michaelis-Menten, 2 compartment, with Vmax as an amount, macro constants
  • Michaelis-Menten, 2 compartment, with Vmax as an amount, micro constants
  • Michaelis-Menten and linear elimination, 2 compartment, macro constants
  • Michaelis-Menten and linear elimination, 2 compartment, micro constants
  • Michaelis-Menten and linear elimination, 2 compartment, with Vmax as an amount, macro constants
  • Michaelis-Menten and linear elimination, 2 compartment, with Vmax as an amount, micro constants
  • Michaelis-Menten, 1 compartment, with enzyme interaction
  • Michaelis-Menten, 1 compartment, 2 analytes, with Vmax as an amount, macro constants

Indices and tables

• Index

• Module Index

• Search Page