Introduction

Tucuxi is a software developed to assist the analysis of drug concentration in blood used for therapeutic drug monitoring in clinical pharmacology.

The analysis depends on the aministrated drug, on the patient’s specific set of parameters, and on the patient’s state during the blood sampling. Computing methods varies between different route administration drug and model chosen.

Tucuxi allows to gather those datas and provides proper dosages adjustments for the treatment analysis of each individual. The software generates graphical informations on concentrations measured and predicted, given the patient’s covariates and targets figured by the specialist.

The process of a treatment analysis with Tucuxi is presented as a flow gathering different steps. The interface of the software is seperated in three parts, including the process panel on the top, allowing to navigate between steps. The two parts below is used to apply changes or set parameters with the control panel and to display informations about the measured concentration to analyze in the graph area. After the specialist’s validation, a report is generated and presents every element necessary to the therapeutic drug monitoring of a patient.

The software is developed and maintained by the REDS institute, from the HEIG-VD in collaboration with the CHUV.